Von Willebrand factor test
Quick answer: This test measures von Willebrand factor, a blood protein that helps platelets stick together and form a clot. Doctors order it for easy bruising, frequent nosebleeds or heavy periods to check for von Willebrand disease.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed; tell staff about any blood thinners or hormone pills you take.
- In fertility careVon Willebrand disease is a common cause of heavy menstrual bleeding and needs planning before pregnancy and delivery.
How the test is done
- 1Blood is drawn into light-blue citrate tubes
- 2The tubes are filled exactly and mixed gently
- 3The lab measures the amount and activity of von Willebrand factor
- 4Factor VIII is often measured from the same sample
What your results can mean
Reading your report
Stress, exercise, hormones and pregnancy can raise levels, so the test is sometimes repeated; discuss it with your doctor.
If the result is outside the usual range
Low levels can point to von Willebrand disease, the most common inherited bleeding disorder, which can cause heavy periods and easy bruising. Levels rise with stress, exercise, pregnancy and hormone use, which can hide a low level.
Who usually has this test
People, especially women with heavy periods, who bruise easily, have frequent nosebleeds or bleed a lot after surgery or childbirth.
Risks and aftercare
Bruising is possible, so press firmly on the site for a few minutes.
Names and options
Also called: VWF test, vWF antigen, von Willebrand disease test
Listed by the hospital as
- VON WILLEBRAND FACTOR (VWF), CITRATE PLASMA
Questions about this test
Can heavy periods be due to von Willebrand disease?
Yes, heavy periods from the first period onwards are a common sign in women. Testing is often advised if heavy bleeding comes with other bleeding signs.
Why might I need to repeat this test?
Levels change with stress, illness, exercise, pregnancy and the menstrual cycle. A single normal result may not rule out the condition.
Does blood group affect the result?
Yes, people with blood group O naturally have lower levels. Doctors take this into account when reading results.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
Get directions ↗IVF Pulse fertility care at Tamara Hospital →
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.