Buccal smear examination
Quick answer: A buccal smear examination looks at cells gently scraped from the inside of the cheek under a microscope. Your doctor will explain why it has been requested; it is sometimes used as a simple screening check of cells.
- SampleSwab
- TakesA few minutes
- Before the testYou may be asked to rinse your mouth with water before the sample is taken.
How the test is done
- 1You may be asked to rinse your mouth with water first
- 2The inside of your cheek is gently scraped with a wooden spatula or brush
- 3The cells are spread on a glass slide and fixed
- 4Ask the hospital what this test is being used for in your case
What your results can mean
Reading your report
A pathologist examines the cells under a microscope and writes a report; discuss what it means for you with your doctor.
If the result is outside the usual range
The lab looks at the cells under a microscope and reports what it sees. What the result means depends on why it was requested, so ask your doctor to explain it.
Who usually has this test
People whose doctor has specifically requested it; ask the hospital or your doctor what the test is for in your case.
Risks and aftercare
There is no special aftercare, and the cheek may feel slightly scratched for a short time.
Names and options
Also called: buccal smear, cheek swab cytology, Barr body test
Listed by the hospital as
- BUCCAL SMEAR EXAMINAION
Questions about this test
Does a buccal smear hurt?
No, most people only feel a light scraping inside the cheek. It takes a few seconds.
What is a buccal smear used for?
It can be used for different purposes depending on what the doctor wants to check. Ask the hospital or your doctor what it is for in your case.
Do I need to avoid eating before a buccal smear?
You may be asked to rinse your mouth or avoid eating just before, so food does not mix with the cells. Follow the instructions you are given.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.