Methionine screening test
Quick answer: This blood test measures methionine, an amino acid, as a screen for some inherited metabolic conditions. Doctors may order it when an inherited problem with amino acid processing, such as homocystinuria, is suspected.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1You are seated and a vein in your arm is chosen
- 2The skin is cleaned and a needle draws blood
- 3For babies, a few drops may be taken from a heel prick instead
- 4The sample is sent for amino acid testing
What your results can mean
Reading your report
An abnormal screen usually needs further specialist tests; discuss the result with your doctor.
If the result is outside the usual range
A high methionine level can be seen with some inherited conditions such as homocystinuria, with liver disease, or with a high-protein diet in infants. Ask the hospital what this test is for in your case, as screening results need specialist follow-up.
Who usually has this test
Babies and children suspected of an inherited metabolic condition, and people whose doctor wants to look into amino acid processing.
Risks and aftercare
A small bruise or heel soreness may occur and usually settles quickly.
Names and options
Also called: methionine level, amino acid screening
Listed by the hospital as
- METHIONINE SCREENING, SERUM
Questions about this test
What is homocystinuria?
Homocystinuria is a rare inherited condition in which the body cannot break down certain amino acids properly. It can affect the eyes, bones, blood vessels and learning. A specialist uses several tests, not just methionine, to diagnose it.
Is methionine screening part of newborn screening?
In some newborn screening programmes, methionine is one of the markers checked. Programmes in India differ between hospitals, so ask the hospital what their screening includes.
What happens if the methionine screen is abnormal?
An abnormal screen does not confirm a condition. Your doctor will usually arrange further blood or urine tests and may refer you to a metabolic or genetics specialist.
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Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.