Lipoprotein electrophoresis
Quick answer: Lipoprotein electrophoresis separates the different fat-carrying particles in your blood to show their pattern. It is occasionally used to identify inherited types of very high cholesterol or triglycerides.
- SampleBlood
- TakesAbout 5 minutes for the blood draw
- Before the testYou may be asked to fast beforehand; follow the lab's instructions.
How the test is done
- 1Staff check that you have fasted if asked
- 2A vein in your arm is cleaned
- 3Blood is drawn into a tube
- 4In the lab, the fat-carrying particles are separated on a gel to show their pattern
What your results can mean
Reading your report
Normal ranges differ between labs, so compare your result with the range printed on your report and discuss it with your doctor.
If the result is outside the usual range
An abnormal pattern can point to an inherited type of high cholesterol or triglycerides, or to changes caused by diabetes, thyroid, kidney or liver problems. The report describes which particle groups are raised or reduced.
Who usually has this test
People with very high cholesterol or triglycerides, especially with a family history, where doctors want to know the type of lipid disorder.
Risks and aftercare
You may have mild soreness at the needle site for a short time.
Names and options
Also called: lipoprotein typing, lipid electrophoresis
Listed by the hospital as
- LIPOPROTEIN ELECTROPHORESIS, SERUM
Questions about this test
Why would I need lipoprotein electrophoresis if I already had a lipid profile?
A lipid profile gives the amounts of cholesterol and triglycerides. Electrophoresis shows the pattern of the particles that carry them, which can help identify some inherited lipid disorders. It is only needed in specific situations.
Is lipoprotein electrophoresis commonly done?
No. It is an older specialist test that is now used less often, as most decisions can be made from a standard lipid profile and other tests. Your doctor will explain why they have asked for it.
Can diabetes or thyroid problems change the result?
Yes. Poorly controlled diabetes, an underactive thyroid, kidney disease and some medicines can change the lipoprotein pattern. Doctors usually check for these before deciding a pattern is inherited.
Related tests
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.