Haemoglobin electrophoresis (thalassaemia test)
Quick answer: This test separates the types of haemoglobin in your blood to find abnormal forms, such as those in thalassaemia and sickle cell disease. It is used to check for thalassaemia trait, sickle cell and other haemoglobin disorders, often when red cells are small.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed; tell staff if you have had a blood transfusion in the last few months.
- In fertility careThalassaemia trait is common in India, and testing both partners before or early in pregnancy shows whether the baby could be at risk.
How the test is done
- 1Blood is drawn into a purple-top tube
- 2No fasting is needed
- 3The lab separates haemoglobin types, often by HPLC or electrophoresis
- 4The share of HbA, HbA2, HbF and any abnormal types is reported
What your results can mean
Reading your report
Iron deficiency can affect some results, so your doctor will read them with your iron tests; discuss any abnormal result with them.
If the result is outside the usual range
A raised HbA2 can point to beta thalassaemia trait, and abnormal bands can point to sickle cell, HbE or other variants. Iron deficiency can lower HbA2 and hide thalassaemia trait.
Who usually has this test
Couples planning pregnancy, women early in pregnancy, and people with small red cells not explained by lack of iron.
Risks and aftercare
Bruising is possible; genetic counselling is advised if a trait is found.
Names and options
Also called: Hb electrophoresis, HPLC for thalassaemia, thalassaemia screening, Hb variant test
Listed by the hospital as
- HAEMOGLOBIN ELECTROPHORESIS
Questions about this test
Why should both partners be tested for thalassaemia?
If both carry thalassaemia trait, each pregnancy has a one in four chance of a baby with thalassaemia major. Testing both helps plan your options.
Can iron deficiency affect the result?
Yes, lack of iron can lower HbA2 and hide beta thalassaemia trait. Doctors may treat the iron lack and retest.
Is thalassaemia common in India?
Thalassaemia trait is common in India, with higher rates in some communities. Screening before or early in pregnancy is widely advised.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
Get directions ↗IVF Pulse fertility care at Tamara Hospital →
Reception
Waiting area
IVF lab
This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.