CD4 and CD8 count
Quick answer: This test counts CD4 and CD8 cells, two types of T lymphocytes that are central to the immune system. It is mainly used to check immune health and guide care in people with HIV, and in some other immune conditions.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1Blood is drawn into an EDTA tube
- 2The sample is kept at room temperature, not refrigerated
- 3The lab uses flow cytometry to count CD4 and CD8 cells
- 4Results are given as counts and a CD4 to CD8 ratio
What your results can mean
Reading your report
Counts vary from day to day and with illness, so trends matter more than one result; discuss them with your doctor.
If the result is outside the usual range
A low CD4 count can point to weakened immunity, most often from HIV, and helps guide treatment and infection prevention. CD8 and the ratio can change with viral infections and other immune conditions.
Who usually has this test
People living with HIV, and some people with other immune problems or on medicines that affect immunity.
Risks and aftercare
Bruising is possible; keep taking your HIV treatment as prescribed.
Names and options
Also called: CD4 count, CD8 count, CD4/CD8 ratio, T cell count
Options
- CD4 count
- CD8 count
Listed by the hospital as
- CD4 COUNT, EDTA PLASMA
- CD8 COUNT, EDTA PLASMA
Questions about this test
How often is CD4 checked in HIV?
It is checked at diagnosis and then as your doctor advises, often less often once treatment is working well. Viral load is also used to monitor treatment.
Can a CD4 count change from day to day?
Yes, infections, the time of day and stress can change it. Doctors look at the trend rather than one result.
What does a low CD4 to CD8 ratio mean?
It often reflects immune changes in HIV and some other conditions. Your doctor reads it with your CD4 count.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.