Anti-smooth muscle antibody (ASMA) test
Quick answer: This test checks your blood for antibodies against smooth muscle. Doctors order it to help diagnose autoimmune hepatitis, where the immune system attacks the liver.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1You sit and a band is placed around your upper arm
- 2A needle draws blood from a vein
- 3The sample is checked for smooth muscle antibodies
- 4Your doctor reads the result with your liver tests
What your results can mean
Reading your report
A positive result is read with liver tests and symptoms, so discuss it with your doctor.
If the result is outside the usual range
A positive result can be seen with autoimmune hepatitis, especially at higher levels. Low positive results can also be seen with some viral infections and other conditions, so it is not a diagnosis by itself.
Who usually has this test
People with unexplained liver inflammation or raised liver enzymes, where autoimmune hepatitis is a possibility.
Risks and aftercare
Slight bruising is possible at the needle site.
Names and options
Also called: ASMA, smooth muscle antibody
Listed by the hospital as
- ANTI SMOOTH MUSCLE ANTIBODY (ASMA)
Questions about this test
What is autoimmune hepatitis?
It is a condition in which the immune system attacks the liver, causing inflammation. It can be treated, so finding it early matters.
Can I have a positive ASMA without liver disease?
Yes. Low levels can appear with viral infections and in some healthy people. Your doctor looks at your liver tests and other antibodies.
What other tests are done with ASMA?
Doctors often check ANA, IgG levels and liver function tests, and sometimes a liver biopsy, to confirm autoimmune hepatitis.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.