TSH receptor antibody (TRAb) test
Quick answer: This test looks for antibodies that attach to the TSH receptor on the thyroid gland, which can make it overactive. It helps doctors diagnose Graves' disease and decide on treatment for an overactive thyroid.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
- In fertility careIn pregnancy these antibodies can cross the placenta and affect the baby's thyroid, so they are checked in women with current or past Graves' disease.
How the test is done
- 1Blood is drawn from a vein in your arm
- 2No fasting is needed
- 3The lab measures antibodies that bind the TSH receptor
- 4Results are read with thyroid hormone tests
What your results can mean
Reading your report
Results are read with your TSH and thyroid hormone levels; discuss them with your doctor.
If the result is outside the usual range
A raised level can point to Graves' disease, a common cause of an overactive thyroid. In pregnancy, high levels can cross the placenta and affect the baby's thyroid.
Who usually has this test
People with an overactive thyroid, and pregnant women with current or past Graves' disease.
Risks and aftercare
Bruising is possible; keep taking any thyroid medicines as prescribed.
Names and options
Also called: TRAb, TSI, thyroid stimulating immunoglobulin, Graves antibody
Listed by the hospital as
- TSH RECEPTOR ANTIBODY
Questions about this test
Why is TRAb tested in pregnancy?
If you have or had Graves' disease, these antibodies can cross the placenta and affect the baby's thyroid. Testing helps your doctors plan monitoring for you and the baby.
Can TRAb stay raised after thyroid treatment?
Yes, levels can stay raised after radioiodine or surgery for Graves' disease. This still matters in pregnancy, even if your own thyroid levels are normal.
Does a negative TRAb rule out Graves' disease?
A negative result makes Graves' disease less likely but does not fully rule it out. Doctors also use thyroid hormone tests and sometimes a scan.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
Get directions ↗IVF Pulse fertility care at Tamara Hospital →
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.