Plasma free metanephrines test
Quick answer: This test measures metanephrines, substances made when the body breaks down adrenaline and noradrenaline. It is one of the main tests used to look for phaeochromocytoma or paraganglioma, rare tumours that make these hormones.
- SampleBlood
- TakesAbout 30 to 45 minutes including the rest
- Before the testFollow the lab's instructions; you may be asked to rest lying down before the sample and avoid caffeine and smoking beforehand.
How the test is done
- 1You avoid caffeine, smoking and heavy exercise beforehand, as advised
- 2A small tube (cannula) may be placed in a vein in your arm
- 3You lie down and rest for about 20 to 30 minutes
- 4Blood is drawn while you are still lying down and sent on ice
What your results can mean
Reading your report
Stress and some medicines can raise levels slightly, so a mildly high result is often repeated; discuss it with your doctor.
If the result is outside the usual range
A clearly high level can point to a phaeochromocytoma or paraganglioma, rare tumours that make adrenaline-type hormones. Mild rises are more often due to stress, posture, caffeine or some medicines.
Who usually has this test
People with spells of headache, sweating and palpitations, very high blood pressure, an adrenal lump on a scan, or a family history of these tumours.
Risks and aftercare
Bruising is possible, and you can return to normal activity.
Names and options
Also called: metanephrines, normetanephrine, phaeochromocytoma test
Listed by the hospital as
- METANEPHRINE- FREE, EDTA PLASMA
Questions about this test
Why must I lie down before the blood draw?
Standing up raises noradrenaline and its breakdown products. Resting lying down lowers the chance of a falsely high result.
Which medicines can affect the result?
Some antidepressants, decongestants and blood pressure medicines can raise metanephrines. Tell your doctor about all your medicines, but do not stop any without advice.
Is a urine test an option instead?
Yes, a 24-hour urine test for metanephrines or catecholamines is another way to check. Your doctor will choose which suits your situation.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
Get directions ↗IVF Pulse fertility care at Tamara Hospital →
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.