LE cell test
Quick answer: The LE cell test looks under a microscope for a type of white cell that is seen in lupus (systemic lupus erythematosus). It is an older test for lupus; antinuclear antibody (ANA) and related blood tests are now preferred.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1Blood is drawn from a vein
- 2In the lab, some white cells are damaged on purpose and the sample is incubated
- 3A smear is made and stained
- 4The lab looks for typical LE cells under the microscope
What your results can mean
Reading your report
A negative result does not rule out lupus; discuss further tests with your doctor.
If the result is outside the usual range
LE cells can be seen with lupus, but also with some other autoimmune conditions and some medicines. A negative result does not rule out lupus, as this test misses many cases.
Who usually has this test
People with possible lupus, though most doctors now use ANA and anti-dsDNA blood tests instead.
Risks and aftercare
Bruising is possible where the blood was drawn.
Names and options
Also called: lupus erythematosus cell test, LE cell
Listed by the hospital as
- LE CELL DETECTION, BLOOD
Questions about this test
Is the LE cell test still used?
It has largely been replaced by antibody tests such as ANA, which pick up lupus more often. Some labs still offer it.
Can lupus affect pregnancy?
Lupus can raise the risk of miscarriage and other complications. Planning pregnancy when the disease is quiet, with specialist care, helps.
Can medicines cause LE cells?
Some medicines can cause a lupus-like condition and a positive result. Tell your doctor about your medicines, but do not stop any on your own.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
Get directions ↗IVF Pulse fertility care at Tamara Hospital →
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.