Anti-LC-1 (liver cytosol type 1) antibody test
Quick answer: This blood test looks for antibodies against liver cytosol type 1, a liver protein. Doctors usually order it as part of the work-up for autoimmune hepatitis, mainly type 2.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1You sit and your arm is supported
- 2A vein is cleaned and a needle inserted
- 3Blood is collected into one tube
- 4The lab tests for antibodies to liver cytosol type 1
What your results can mean
Reading your report
A positive result does not by itself confirm a disease, because some healthy people test positive; your doctor reads it with your symptoms and other tests.
If the result is outside the usual range
A positive result can be seen with autoimmune hepatitis type 2, which is more common in children and young people, often along with LKM-1 antibodies. It is sometimes seen with hepatitis C.
Who usually has this test
Children, young adults and others with unexplained liver inflammation when autoimmune hepatitis is being considered.
Risks and aftercare
Expect at most a small bruise; the result is usually discussed together with your other liver tests.
Names and options
Also called: LC-1, liver cytosol antibody
Listed by the hospital as
- LC-1, SERUM
Questions about this test
What is autoimmune hepatitis type 2?
It is a form of autoimmune liver inflammation marked by LKM-1 or LC-1 antibodies. It often starts in childhood and can be more active than type 1.
Can LC-1 levels show how active the liver disease is?
Some studies suggest LC-1 levels move with disease activity, but doctors rely mainly on liver blood tests and symptoms to judge this.
Is LC-1 tested on its own?
It is usually part of a wider liver antibody panel. Testing it alone is uncommon.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.