Faecal calprotectin test
Quick answer: This stool test measures calprotectin, a protein released when there is inflammation in the bowel. Doctors order it to help tell inflammatory bowel disease, such as Crohn's or ulcerative colitis, apart from irritable bowel syndrome, and to monitor it.
- SampleStool
- TakesOnly the time it takes to collect a sample
- Before the testCollect a stool sample in the container given; tell your doctor about any regular painkillers, as some can raise the level.
How the test is done
- 1You are given a labelled stool container
- 2Collect a small sample of stool without urine or toilet water
- 3Fill only the amount marked on the container
- 4Hand in the sample promptly so the lab can measure calprotectin
What your results can mean
Reading your report
Ranges and cut-offs differ between labs and methods, so discuss your result with your doctor.
If the result is outside the usual range
A raised level can point to inflammation in the bowel, such as Crohn's disease or ulcerative colitis, and can also be seen with infections or some painkillers. A normal level makes inflammatory bowel disease less likely and points more towards irritable bowel syndrome.
Who usually has this test
People with long-term diarrhoea, belly pain or blood in the stool, and people with known inflammatory bowel disease being monitored.
Risks and aftercare
No risks or discomfort; just wash your hands after collecting the sample.
Names and options
Also called: calprotectin, stool calprotectin, fecal calprotectin
Listed by the hospital as
- FECAL CALPROTECTIN, STOOL
Questions about this test
Can calprotectin tell IBS from IBD?
It helps. A normal level makes inflammatory bowel disease unlikely, while a raised level suggests inflammation that may need further tests such as colonoscopy.
Can a stomach bug raise calprotectin?
Yes. Gut infections can raise it for a while. Your doctor may repeat the test after you have recovered.
How is calprotectin used in Crohn's or colitis?
Doctors use it to track inflammation over time. A rising level can be an early sign of a flare.
Related tests
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.