Anti-GAD65 antibody test
Quick answer: This test looks for antibodies against GAD65, a protein in insulin-making cells of the pancreas. It helps doctors tell type 1 or autoimmune diabetes apart from type 2 diabetes; it is also used in some rare nerve conditions.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1Blood is drawn from your arm
- 2No fasting is usually needed
- 3The lab measures antibodies against GAD65
- 4Results are often read with other diabetes antibodies such as IA-2
What your results can mean
Reading your report
A positive result suggests the immune system is attacking the pancreas; discuss what it means with your doctor.
If the result is outside the usual range
A positive result can point to type 1 diabetes or a slow-onset form in adults called LADA. GAD65 antibodies are also linked with some rare nerve conditions, such as stiff person syndrome.
Who usually has this test
People newly diagnosed with diabetes where the type is unclear, especially young or lean adults.
Risks and aftercare
Bruising is possible; keep following your current diabetes treatment.
Names and options
Also called: GAD antibody, GADA, glutamic acid decarboxylase antibody
Listed by the hospital as
- ANTI GAD 65 ANTIBODY, SERUM
Questions about this test
What is LADA?
LADA stands for latent autoimmune diabetes in adults. It is a slow form of autoimmune diabetes that can first look like type 2 and later need insulin.
Does a negative result rule out type 1 diabetes?
No, some people with type 1 diabetes do not have GAD65 antibodies. Doctors may test other antibodies and look at the overall picture.
Can relatives of people with type 1 diabetes be tested?
Antibody testing can show a raised risk in relatives, usually in research or specialist settings. Ask your doctor whether it is useful for you.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.