Anti-DNase B test
Quick answer: This blood test measures antibodies against DNase B, an enzyme made by group A streptococcus bacteria. Doctors usually order it with ASO to show a recent strep infection, for example when rheumatic fever or kidney inflammation after strep is suspected.
- SampleBlood
- TakesAbout 5 minutes
- Before the testNo special preparation is usually needed.
How the test is done
- 1You are seated and your sleeve rolled up
- 2A vein on your arm is cleaned
- 3A needle draws a tube of blood
- 4The lab measures antibodies to the strep enzyme DNase B
What your results can mean
Reading your report
Levels stay raised for weeks after an infection and normal levels differ by age, so discuss your result with your doctor.
If the result is outside the usual range
A raised level can show a recent group A strep infection, including skin infections, and supports a diagnosis of rheumatic fever or post-strep kidney inflammation. Normal levels vary with age.
Who usually has this test
Children and adults with joint pain, heart murmur, swelling or dark urine a few weeks after a sore throat or skin infection.
Risks and aftercare
A small bruise is possible; children may want a little comfort afterwards.
Names and options
Also called: ADB, anti-deoxyribonuclease B, strep antibody
Listed by the hospital as
- ANTI DNASE B
Questions about this test
How is anti-DNase B different from ASO?
Both show a recent strep infection. Anti-DNase B stays raised longer and rises after skin infections too, where ASO may not, so the two are often tested together.
Can this test diagnose a current strep throat?
No. It shows a recent past infection. A throat swab is used to check for an infection happening now.
Why might the test be repeated?
A rising level between two samples taken a couple of weeks apart gives stronger evidence of a recent infection than a single result.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
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This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.