HOMA-IR (insulin resistance index)
Quick answer: HOMA-IR is a calculation from your fasting glucose and fasting insulin that estimates insulin resistance. Doctors use it to check for insulin resistance, for example in PCOS, obesity or prediabetes.
- SampleBlood
- TakesAbout 5 minutes
- Before the testFast for 8 to 12 hours (water is fine) before the test.
- In fertility careInsulin resistance is common in PCOS and can affect ovulation.
How the test is done
- 1You fast for 8 to 12 hours, drinking only water
- 2You come in the morning before eating
- 3One blood sample is taken for glucose and insulin
- 4HOMA-IR is calculated from the two results
What your results can mean
Reading your report
There is no single agreed cut-off and methods differ between labs, so discuss your result with your doctor.
If the result is outside the usual range
A high HOMA-IR can point to insulin resistance, which can be seen with PCOS, being overweight, prediabetes and fatty liver. Cut-offs vary, so your doctor reads it with your other results.
Who usually has this test
Women with PCOS, people who are overweight or have prediabetes, and people with a family history of type 2 diabetes.
Risks and aftercare
Eat once the sample is taken.
Names and options
Also called: HOMA IR, HOMA2-IR, insulin resistance test
Listed by the hospital as
- HOMA2-IR INDEX
Questions about this test
Why is HOMA-IR checked in PCOS?
Insulin resistance is common in PCOS and can affect ovulation and weight. Finding it helps guide lifestyle changes and treatment.
Is HOMA-IR a diagnosis?
No. It is an estimate of insulin resistance. Diabetes is diagnosed with other tests such as fasting sugar or HbA1c.
Can lifestyle changes improve HOMA-IR?
Yes. Regular activity, a balanced diet and weight loss if needed can improve insulin resistance.
Related tests
Tamara Hospital & IVF Centre, Rajajinagar
34/3, 10th Cross Road, opp. Vardhaka Sardar Patel School, 1st N Block, 2nd Stage, Rajajinagar, Bengaluru 560010
The hospital is open 24 hours. Call before you come to check the timing for your scan or sample collection.
Get directions ↗IVF Pulse fertility care at Tamara Hospital →
Reception
Waiting area
IVF lab
This page explains each test in general terms so you know what to expect. It is not medical advice: your doctor decides which tests you need and what your results mean. Reference ranges differ between laboratories. Updated 4 November 2026.