Home / Calculators / Ovarian response / Ovarian sensitivity index
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A calculator sees three or four figures. A specialist sees your history, your scans, your partner's results, and how you actually responded to treatment. If you're between cycles, changing clinics, or something in your results doesn't add up, a second opinion is the fastest way to find out whether anything would be done differently.
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These tools provide general information and are not a diagnosis or a substitute for assessment by a qualified clinician. Reference ranges and sources are stated on each calculator. Predictive estimates describe groups of people and cannot predict an individual outcome.
A calculator sees three or four figures. A specialist sees your history, your scans, your partner's results, and how you actually responded to treatment. If you're between cycles, changing clinics, or something in your results doesn't add up, a second opinion is the fastest way to find out whether anything would be done differently.
Free first consultation. No obligation to start treatment, and it doesn't affect your care at your current clinic.
Eggs retrieved relative to the total gonadotropin dose used.
Exact calculationArithmetic on the numbers you enter. If your inputs are right, this figure is right.
The ovarian sensitivity index is oocytes retrieved per 1000 IU of gonadotropin, separating a good response from an expensive one. Below about 1.7 indicates low sensitivity regardless of how many eggs were collected.
Source — OSI is calculated as oocytes retrieved divided by total FSH dose, multiplied by 1000. Cut-offs vary between publications.
Total collected
Sum across the cycle
That falls in the 1.7–5 band.
Your result of 4.89 per 1000 IU sits in the highlighted band. Bands are reference points used alongside clinical findings — not a diagnosis.
Within the range most cycles fall into.
OSI is calculated as oocytes retrieved divided by total FSH dose, multiplied by 1000. Cut-offs vary between publications.
Highlighted is the stage this measurement belongs to. It is a map of the process, not a schedule — timings vary by protocol and by clinic.
Because ten eggs on 1,500 IU and ten on 4,500 IU are very different cycles. OSI captures the cost of the response, which is what informs the next protocol.
It can. A high OSI sometimes prompts a lower starting dose next cycle specifically to reduce the chance of ovarian hyperstimulation.
Not necessarily — it may mean your ovaries are less sensitive, which is information rather than error. What it does prompt is a conversation about whether a higher dose would help or simply cost more without changing the yield.
A calculator sees three or four figures. A specialist sees your history, your scans, your partner's results, and how you actually responded to treatment. If you're between cycles, changing clinics, or something in your results doesn't add up, a second opinion is the fastest way to find out whether anything would be done differently.
Free first consultation. No obligation to start treatment, and it doesn't affect your care at your current clinic.
OSI informs protocol planning and is interpreted by a clinician alongside your monitoring data. Nothing here is a diagnosis or a substitute for assessment by a clinician.
A calculator gives you a number. These explain what it means, and what it does not.
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