Informational only - Not a substitute for medical advice
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A systematic review of eight studies covering 2,267 patients found no clear benefit from hysteroscopic polyp resection for clinical pregnancy, live birth, miscarriage or implantation in IVF or ICSI. Polyps under 20 mm appear to have no measurable impact on IVF outcomes.
An endometrial polyp is an overgrowth of the lining of the womb, attached to the wall and projecting into the cavity. Most are benign, many cause no symptoms, and they are frequently found incidentally on a scan done for another reason.
They are common, and being told you have one is not in itself alarming news. The question that follows — whether it needs removing before IVF — is where the evidence becomes more interesting than the diagnosis.
Polyps are usually picked up on ultrasound and confirmed at hysteroscopy, which is also how they are removed. Our overview of hysteroscopy in the infertility workup covers the procedure itself.
For smaller polyps, the evidence suggests not. Endometrial polyps under 20 mm appear to have no measurable impact on IVF outcomes, and polyps under 15 mm found before an ICSI cycle have been reported not to require intervention.
That runs against the intuition that anything in the cavity must interfere with implantation. For larger polyps the position is less settled, and the honest answer is that the size at which a polyp starts to matter has not been established by good trials.
It also runs against how the finding is often communicated. Being told a polyp has been found, in the context of fertility treatment, tends to imply that it is the reason treatment has not worked. For a small polyp, the evidence does not support that inference. Our article on whether uterine polyps cause infertility looks at the wider question.
Not demonstrably, for IVF. A systematic review of eight studies covering 2,267 patients found no clear benefit from hysteroscopic polyp resection for clinical pregnancy, live birth, miscarriage or implantation rates in IVF or ICSI cycles.
The same review did find that resecting polyps under 2 cm may be associated with improved clinical pregnancy rates after intrauterine insemination. IUI and IVF are different treatments, and a benefit in one does not carry over to the other.
The evidence base itself is weak, and that should be said plainly rather than buried. The authors could not perform a meta-analysis because of significant heterogeneity between studies and a lack of randomised trials. This is not a settled question with a clear answer; it is an unsettled question where surgery is nonetheless routinely offered.
Absence of demonstrated benefit is not the same as demonstrated absence of benefit. It does mean that anyone presenting polypectomy before IVF as clearly established is going beyond what has been shown.
It is worth understanding why the IUI and IVF findings might genuinely differ rather than being a quirk of the data. In IUI, sperm are placed in the uterus and everything that follows happens in the body, so anything occupying the cavity has a longer stretch of the process to interfere with.
In IVF, fertilisation and early development happen in the laboratory and an embryo is placed directly. The two treatments expose the cavity to different demands.
That is a hypothesis rather than an established mechanism. It is offered here because the alternative — assuming a finding in one treatment must apply to the other — is how IUI evidence ends up being quoted at IVF patients.
It appears to. Polyps under 20 mm have been reported to have no impact on IVF outcomes, and one report went further, suggesting that resecting a polyp under 15 mm before ICSI is not required and might even be harmful.
So size is the first thing to establish about your own polyp, and it should be on the scan report as a measurement in millimetres. If the recommendation to operate does not reference that number, it is worth asking what it is based on.
The suggestion that removing a small polyp before ICSI might be harmful deserves particular attention, because it inverts the usual assumption that surgery is at worst neutral. Any instrumentation of the cavity carries some risk to the endometrium, and the procedure delays treatment. Where there is no demonstrated benefit to offset those costs, the balance is not obviously favourable.
This is a single reported finding rather than a settled conclusion, and it should not be read as evidence that polypectomy is dangerous. It is a reason to want a specific justification for a specific polyp, rather than a general policy applied to every finding on a scan.
IVY can read your scan report, look at what was actually found and how large it is, and set out what the published evidence supports for a polyp of that size.
Polyps found during ovarian stimulation, under 15 mm, have been reported not to require any intervention. Stimulation thickens the endometrium considerably, and structures become more visible than they were at baseline.
This matters because the discovery is alarming in the middle of a cycle, when a couple has already committed time, money and injections. The pressure to act is highest at exactly the point where the evidence supports acting least.
Cancelling a cycle is a significant decision. If it is being proposed on the basis of a small polyp found mid-stimulation, that is a decision worth a second opinion before it is taken.
There is also a middle path that is not always offered. A cycle can proceed to egg collection with the embryos frozen rather than transferred, leaving the question of the polyp to be settled before a later transfer.
That preserves the eggs already paid for and grown, and separates the retrieval decision from the transfer decision — which are not the same decision and do not have to be made together.
Whether that suits you depends on your clinic's freezing results and your own circumstances. It is worth asking about specifically, because a straight choice between cancelling and proceeding regardless is a narrower set of options than actually exists.
Hysteroscopic polypectomy is a low-risk procedure, but it is still surgery, it costs money, and it usually delays treatment by at least a cycle. Those costs are certain; the benefit for IVF is not.
None of this argues against polypectomy where there is a reason for it — abnormal bleeding, a large polyp, or a diagnostic question about the cavity. It argues against removal being treated as automatic on a small, incidental finding, which the published evidence does not support.
It is also worth separating two questions that get merged. Whether a polyp should be removed at some point is a gynaecological question, and there can be good reasons unrelated to fertility. Whether it should be removed before this IVF cycle, at the cost of a delay, is a different question with a weaker evidence base.
A clinic answering the first is not necessarily answering the second.
If you have already had a polyp removed before IVF, this is not a reason to think the surgery was a mistake. It is low-risk, it may have been indicated for reasons beyond fertility, and the evidence is uncertain rather than negative. The purpose here is to inform the next decision.
Send IVY your scan report and treatment plan. You will get an independent read on what the finding means, what the evidence supports for that polyp size, and what to ask before agreeing to a delay.
What people ask after a polyp turns up on a scan.
The evidence does not clearly support it. A systematic review of 2,267 patients found no clear benefit from resection for clinical pregnancy, live birth, miscarriage or implantation in IVF or ICSI cycles, and polyps under 20 mm appear not to affect IVF outcomes. There may be other reasons to remove one — bleeding, size, a diagnostic question — but improving IVF success is not well established.
It appears to. Polyps under 20 mm have been reported to have no measurable impact on IVF outcomes, and one report suggested resecting a polyp under 15 mm before ICSI is not required and might be harmful. Above that, the evidence thins out and no reliable threshold has been established. Ask for the measurement in millimetres from your scan report.
Polyps under 15 mm found during ovarian stimulation have been reported not to require intervention. Stimulation thickens the lining and makes structures more visible than at baseline. Cancelling is a significant decision, and if it is being proposed for a small polyp found mid-cycle, that is a reasonable point at which to seek a second opinion.
Polypectomy is low-risk, straightforward and intuitively appealing — something visible in the cavity feels like something to remove. The evidence for a benefit in IVF specifically is weak, with no randomised trials and too much heterogeneity between studies to pool. That does not make removal wrong, but it does mean it should be a reasoned decision rather than an automatic one.