IVF Reads / Does Fertility Acupuncture Work? What the Trials Found
Does Fertility Acupuncture Work? What the Trials Found
Acupuncture does not improve the chance of a live birth from IVF. In a sham-controlled randomised trial of 848 women at 16 centres, live births occurred in 74 of 405 women (18.3%) given acupuncture and 72 of 404 (17.8%) given sham needling, a risk difference of 0.5% (95% CI -4.9 to 5.8) (Smith 2018, JAMA). The 2013 Cochrane review of 20 randomised trials concluded there is no evidence that acupuncture improves live birth or pregnancy rates in assisted conception (Cheong 2013, CD006920). It is low-risk, and a 2025 meta-analysis found no excess of side effects, so choosing it for reasons other than a fertility effect is a reasonable personal decision.
- The distinction that decides the question is sham versus no treatment. Across 11 randomised trials and 3,561 women, acupuncture raised clinical pregnancy against an untreated control group (RR 1.25, 95% CI 1.05-1.50, p=0.013) but not against sham needling (RR 1.01, 95% CI 0.87-1.17, p=0.907), and had no effect on live birth (RR 1.01, 95% CI 0.88-1.15, p=0.930) (Wang 2025, Frontiers in Reproductive Health).
- The 2013 Cochrane review pooled 20 randomised trials and found no benefit for live birth whether needling was done around egg collection (OR 0.87, 95% CI 0.59-1.29, 2 studies, n=464) or around embryo transfer (OR 1.22, 95% CI 0.87-1.70, 8 studies, n=2,505), both rated low-quality evidence, with no effect on pregnancy or miscarriage rates (Cheong 2013, Cochrane CD006920).
- Older sources saying acupuncture on transfer day works are usually citing the 2008 version of that same Cochrane review, which reported OR 1.89 (95% CI 1.29-2.77) for live birth but said the result could be attributed to placebo effect and the small number of women. PubMed marks it UpdateIn 23888428: it has been replaced.
- Safety is the part that holds up. The 2013 Cochrane review found no evidence of significant side effects across its 20 trials. The honest summary is that acupuncture during IVF appears to do little harm rather than that it does good.
- Whether stress treatment helps fertility outcomes at all is unresolved rather than settled. A Cochrane review of 39 studies and 4,925 people undergoing ART declined to pool the results, because only 2 studies reported live birth and every study was at high risk of bias; it rated the effect on live birth or ongoing pregnancy uncertain on very low quality evidence (Verkuijlen 2016, Cochrane CD011034).
- Acupuncture is paid for out of pocket over weeks or months and is not part of an IVF cycle. A clinic that includes it in a package or presents it as raising success rates is going beyond what the trials show.
Does acupuncture improve your chance of a baby with IVF?
No, on the evidence available. The trial that tested this most directly randomised 848 women having a fresh IVF cycle at 16 centres in Australia and New Zealand to real acupuncture or to sham needling placed away from the acupuncture points. Live births occurred in 74 of 405 women given acupuncture and 72 of 404 given sham — 18.3% against 17.8%, a difference of 0.5% with a confidence interval running from -4.9% to 5.8% (Smith 2018, JAMA). The interval includes zero, and it is narrow enough to rule out a large effect in either direction.
The 2013 Cochrane review reached the same place from 20 randomised trials: "There is no evidence that acupuncture improves live birth or pregnancy rates in assisted conception."
That is the answer to the question most people are actually asking. The rest of this page is about why the internet says otherwise, what acupuncture might still be worth to you, and what to do with the money and the weeks if you decide against it.
Why do some studies say it works, then?
Because of what they compared it against. This is the single most useful thing to understand before you pay for anything, and it is not complicated.
A 2025 meta-analysis of 11 randomised trials and 3,561 women ran both comparisons side by side. Against a control group given no treatment, acupuncture around embryo transfer raised the clinical pregnancy rate: risk ratio 1.25, 95% confidence interval 1.05 to 1.50, p=0.013. Against a sham — needling that looks and feels like the real thing but is placed wrongly or does not penetrate — the same analysis found risk ratio 1.01, 95% CI 0.87 to 1.17, p=0.907. Nothing. And on live birth, the outcome that matters, it found risk ratio 1.01, 95% CI 0.88 to 1.15, p=0.930 (Wang 2025, Frontiers in Reproductive Health).
A trial against no treatment cannot separate the needles from everything else in the appointment: lying still for half an hour, being asked how you are, expecting it to help, and knowing you were the one who got the real thing. When those are held constant by a sham, the difference disappears. That is an interpretation of the contrast between the two figures rather than a separately measured result, but the two figures are the ones above and they come from the same 11 trials.
There is also a dated-source problem. Claims that acupuncture on the day of embryo transfer works usually trace back to the 2008 version of the Cochrane review, which did report a benefit for live birth (odds ratio 1.89, 95% CI 1.29 to 2.77) — while saying in the same sentence that it "could be attributed to placebo effect and the small number of women included in the trials". That version was replaced in 2013 by the one quoted above, using more trials. PubMed flags the 2008 record as superseded. Pages still quoting it are quoting a withdrawn conclusion.
What did the Cochrane review actually pool?
It is worth seeing the numbers rather than the headline, because the pooled estimates are not dramatic negatives — they are wide and they straddle no effect.
- Around egg collection: odds ratio 0.87 for live birth, 95% CI 0.59 to 1.29, from 2 studies and 464 women, no heterogeneity, rated low-quality evidence.
- Around embryo transfer: odds ratio 1.22 for live birth, 95% CI 0.87 to 1.70, from 8 studies and 2,505 women, with substantial inconsistency between them (I-squared 69%), also rated low-quality evidence.
- Pregnancy and miscarriage: no evidence of any effect.
- Side effects: no evidence of significant side effects across the 20 included trials.
Low-quality evidence means the true effect could differ from these estimates. It does not mean a benefit is hiding in there: the JAMA trial published five years later randomised 848 women across 16 centres, was properly sham-controlled, and landed on no difference.
Is there any honest reason to book it?
Yes, and it is not the one clinics advertise.
Most people who book acupuncture during treatment are not doing a cost-benefit calculation on live birth rates. They are in the gap between appointments, where nothing is being done and nothing can be hurried, and booking something is a way of not just waiting. That is a real motive and it deserves to be said out loud rather than dressed up as pharmacology.
If that is the reason, the evidence does not stand in your way. The 2013 Cochrane review found no significant side effects across 20 trials. A licensed practitioner using single-use sterile needles is doing something low-risk. Paying for an hour a week in which someone is unhurried and attentive is a legitimate thing to want.
What the evidence will not let you say is that it is raising your chance of a baby, or that skipping it is costing you one. Hold those two things apart and the decision gets easier, not harder.
If the underlying thing you are trying to treat is the strain itself, that is worth naming as its own problem rather than a fertility intervention. Distress during fertility treatment is common and measurable, and what stress does and does not do to conception has been looked at directly.
Not sure what your results mean?
Upload your test results and IVY will explain what has been checked, what it shows, and what usually comes next — including where a figure is missing.
What should you ask before paying for a course of sessions?
Acupuncture is bought in courses, not single visits, and the money leaves slowly. Before the first appointment, get these answered.
- How many sessions are you proposing, over how many weeks, and what does the whole course cost including any herbs or supplements? Total it up before you start, not after.
- What outcome are you treating? If the answer is a higher chance of pregnancy or live birth, ask which sham-controlled trial that comes from. If the answer is that you will feel better able to cope, that is an answer you can assess yourself in three or four visits.
- Are the needles single-use and sterile, and are they disposed of in front of you?
- Will you tell my fertility team what you are doing, and will you avoid prescribing any herb or supplement without telling them? This matters because your IVF drugs are timed to the day and nobody should be adding unlisted compounds into that.
- At what point would you tell me to stop?
And one question for your fertility team rather than the acupuncturist, phrased so it does not put anyone on the defensive: is there anything about my treatment plan that acupuncture or herbal medicine could interfere with, and would you rather I told you before I start? Most will say they have no objection to the needling and a firm objection to unlabelled herbal preparations. That is useful to know in advance.
What the evidence does not establish
This is the part of the page worth reading twice. Each of the following is commonly claimed, including in the previous version of this page, and none of it is supported by the sources cited here.
- That acupuncture improves live birth rates. The opposite is what was found. Live birth 18.3% versus 17.8% against sham in 848 women (Smith 2018); pooled risk ratio 1.01, 95% CI 0.88 to 1.15 across 11 trials (Wang 2025); no evidence of benefit across 20 trials (Cheong 2013). Three independent analyses, same answer.
- That it reduces miscarriage. The 2013 Cochrane review looked at miscarriage as a stated outcome and found no evidence of an effect. No source here supports the claim.
- That it improves sperm count, motility or erectile function. No source retrieved for this page measures acupuncture against any male fertility parameter. The claim is removed rather than softened, and it is not replaced with a hedge.
- That it thickens the endometrium or improves egg quality. These are mechanism stories. Even if a mechanism were real, the outcome trials above would still show it, and they do not. A mechanism with no outcome behind it is not evidence of benefit.
- That treating stress improves fertility outcomes. This one is genuinely open, and it is worth being precise. A Cochrane review of psychological and educational interventions included 39 studies and 4,925 people undergoing ART and declined to pool the results at all, judging that pooling would not give a clinically meaningful estimate. Only 2 of the 39 studies reported live birth and 1 reported ongoing pregnancy, all with substantial drop-out, and every study was at high risk of bias in at least one domain. Its conclusion is that the effect on live birth or ongoing pregnancy is uncertain on very low quality evidence (Verkuijlen 2016, Cochrane CD011034). That is too poor to say, not shown not to work — and it is about counselling and education, not about acupuncture.
- That the 2025 meta-analysis endorses acupuncture. It is sometimes cited that way because of its 1.25 figure against untreated controls. Its own live birth result is 1.01, and its own sham comparison is 1.01. Read the results, not the framing.
- How much a course costs in India. No pricing data was retrieved for this page, so no figure is given. Ask for the full course price in writing.
On the male-factor point, the measured ground is elsewhere: what lifestyle changes have actually been measured in men and what a semen analysis tells you.
Two neighbouring pages take the same approach to other popular add-ons: Ayurveda and fertility, what has actually been tested, and fertility yoga and meditation. A longer list of claims checked against evidence is in fertility myths versus facts, and the same sham-versus-no-treatment problem runs through most of the paid IVF add-ons offered alongside a cycle.
What to do instead of, or alongside, the needles
If you are deciding this week, three things are worth more than the acupuncture question.
- Ask your clinic what is actually limiting your chance in this cycle, and whether anything on that list is modifiable. A specific answer beats a general intervention.
- If either of you has a semen analysis in the file, ask when it was done and whether it should be repeated. Sperm in any given sample was made over the preceding weeks, which is why a repeat is usually left about three months rather than done straight away.
- Decide the acupuncture question on its own terms — cost, time, how it makes you feel — and not as a bet on the outcome. The trials have taken that part of the decision off the table.
Sometimes the answer is testing, timing or a simpler treatment rather than another thing added on top. That is not a lesser answer.
Want your own cycle explained?
IVY can read your reports alongside your history and set out what the evidence supports for your situation — and what it does not.
Keep reading
5 Sources
- Cheong YC, Dix S, Hung Yu Ng E, Ledger WL. Acupuncture and assisted reproductive technology. Cochrane Database of Systematic Reviews 2013;(7):CD006920. 20 randomised trials. No benefit for live birth around oocyte retrieval (OR 0.87, 95% CI 0.59-1.29, 2 studies, n=464) or around embryo transfer (OR 1.22, 95% CI 0.87-1.70, 8 studies, n=2,505, I-squared 69%), both low-quality evidence; no effect on pregnancy or miscarriage; no evidence of significant side effects. Authors' conclusion: there is no evidence that acupuncture improves live birth or pregnancy rates in assisted conception. Supersedes the 2008 version. PMID 23888428 Cochrane Database of Systematic Reviews
- Smith CA, de Lacey S, Chapman M, Ratcliffe J, et al. Effect of acupuncture vs sham acupuncture on live births among women undergoing in vitro fertilization: a randomized clinical trial. JAMA 2018;319(19):1990-1998. 848 women, 16 IVF centres in Australia and New Zealand. Live birth 74/405 (18.3%) with acupuncture vs 72/404 (17.8%) with sham; risk difference 0.5% (95% CI -4.9 to 5.8); relative risk 1.02 (95% CI 0.76-1.38). PMID 29800212 JAMA
- Wang Y, Ji J, Duan N, Yin Y. Acupuncture as an adjunctive therapy on embryo transfer day: a systematic review and meta-analysis of clinical pregnancy and live birth outcomes. Frontiers in Reproductive Health 2025;7:1673144. 11 randomised trials, 3,561 women. Clinical pregnancy vs untreated control RR 1.25 (95% CI 1.05-1.50, p=0.013); vs sham acupuncture RR 1.01 (95% CI 0.87-1.17, p=0.907); live birth RR 1.01 (95% CI 0.88-1.15, p=0.930). PMID 41064015 Frontiers in Reproductive Health
- Verkuijlen J, Verhaak C, Nelen WL, Wilkinson J. Psychological and educational interventions for subfertile men and women. Cochrane Database of Systematic Reviews 2016;3:CD011034. 39 studies, 4,925 participants undergoing ART. The reviewers judged the studies too dissimilar to pool; only 2 studies reported live birth and 1 reported ongoing pregnancy, all with substantial attrition, and all studies were at high risk of bias in at least one domain. Effects on mental health and on live birth or ongoing pregnancy rated uncertain due to very low quality evidence. PMID 27031818 Cochrane Database of Systematic Reviews
- SUPERSEDED, cited here only to show where the claim came from: Cheong YC, Hung Yu Ng E, Ledger WL. Acupuncture and assisted conception. Cochrane Database of Systematic Reviews 2008;(4):CD006920. Reported a live birth benefit for acupuncture on the day of embryo transfer (OR 1.89, 95% CI 1.29-2.77) while stating the result could be attributed to placebo effect and the small number of women included. The PubMed record carries UpdateIn 23888428: it was replaced by the 2013 version, which found no benefit. PMID 18843737 Cochrane Database of Systematic Reviews
Frequently asked questions
Common questions on this topic.
Is acupuncture during IVF dangerous?
Nothing in the trials cited on this page suggests it is. The 2013 Cochrane review of 20 randomised trials found no evidence of significant side effects, and the 848-woman JAMA trial reported no difference in live birth between real and sham needling rather than any harm. The usual precautions apply: a licensed practitioner, single-use sterile needles, and telling your fertility team what you are doing, particularly if any herbal preparation is being offered alongside.
How many sessions did the trials actually use?
Far fewer than most courses being sold. The 848-woman JAMA trial gave three treatments in total: one between days 6 and 8 of follicle stimulation, then one before and one after embryo transfer. The trials pooled in the 2013 Cochrane review were similarly clustered around egg collection or embryo transfer, and the 2025 meta-analysis was specifically about the embryo transfer day. No source retrieved for this page tested weekly sessions over three to six months, so there is no evidence that a longer course does more — the dose-response question has not been asked.
Is a placebo effect the same as it not working?
For this decision, close enough to matter. A placebo effect is real in the sense that people report feeling different; what it is not is a change in the biological outcome. The reason to care about the distinction here is that live birth is not a reported feeling — a baby either arrives or does not. When the comparison held the ritual constant and varied only the needling, the live birth figures were 18.3% against 17.8%. So if what you are buying is the experience, the sham result does not take that away from you. If what you are buying is a better chance, that is the thing the sham result removes.
What if acupuncture is included in my IVF package price?
Then ask what the package would cost without it, and ask on what basis it was included. A package that presents acupuncture as improving success rates is making a claim the trials cited here do not support, and that is worth knowing about the clinic as well as about the acupuncture. If the answer is that patients like having it available, that is a fair answer — it is just not a clinical one.
What about acupuncture while trying naturally rather than during IVF?
The evidence cited here is all from assisted reproduction cycles, so it does not directly answer that. There is no sham-controlled trial retrieved for this page that measures acupuncture against live birth in couples trying to conceive without treatment. The honest position is that this has not been properly tested, which is weaker ground than the IVF question, not stronger.

